Update on primary mucosal melanoma.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24815565.
- Also identified by DOI 10.1016/j.jaad.2014.03.031.
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Abstract
Mucosal melanomas are aggressive cancers of mucosal surfaces with clinical and pathologic characteristics distinct from cutaneous melanomas, warranting different staging systems and treatment approaches. Surgical resection is performed frequently for the primary tumor, although the utility of lymph node surgery and radiation therapy is not established. Therapies targeted against C-KIT activating mutations, identified in many mucosal melanomas, are emerging as promising treatments.
Medical subject headings
- Gastrointestinal Neoplasms
- Head and Neck Neoplasms
- Melanoma
- Mucous Membrane
- Urogenital Neoplasms