Early-onset acral basal cell carcinomas in Gorlin syndrome.

Torrelo, A; Vicente, A; Navarro, L; Planaguma, M; Bueno, E; González-Sarmiento, R; Hernández-Martín, A; Noguera-Morel, L et al. · Br J Dermatol · 2014

case_report · Level V

Where this comes from

Abstract

Two patients are reported in whom early-onset, distal papules with a histopathological diagnosis of basal cell carcinoma were the first manifestation of Gorlin syndrome (GS). These lesions showed no progression and remained stable through follow-up. Two different PTCH1 gene mutations were detected in the two patients, and thus a phenotype-genotype correlation of this manifestation of GS was not possible.

Medical subject headings