The use of skin substitutes in the treatment of the hand and upper extremity.

Capo, John T; Kokko, Kyle P; Rizzo, Marco; Adams, Julie E; Shamian, Ben; Abernathie, Brenon; Melamed, Eitan · Hand (N Y) · 2014

review · Level V

Where this comes from

Abstract

The introduction of skin substitutes in the last decade has dramatically changed how we think about the concept of "non-healing" wounds. Their use has improved prognosis and reduced morbidity in the treatment of open wounds. This article aims to summarize the development of tissue-engineered skin substitutes, discuss their use, and highlight some specific applications in different clinical settings.

Anatomy