Stem cell responses to nanotopography.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24853234.
- Also identified by DOI 10.1002/jbm.a.35236.
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Abstract
Cells interact with various nanoscaled topographical and biochemical cues in their cellular macromolecular environment. Nanotopography recreates or mimic the cellular macromolecular environment in vitro. The influence of material surface topography on the behavior of adherent cells has been studied. Current techniques enable various kinds of nanopatterned surface to be generated and applied to cells. The purpose of this review is to provide an overview of nanotopography and its surface patterns, and introduce nanotopography effects on cell behavior including cell attachment, proliferation, and cell differentiation with particular emphasis on musculoskeletal regeneration.
Medical subject headings
- Cell Differentiation
- Cell Proliferation
- Nanostructures
- Nanotechnology
- Regeneration
- Stem Cells