Die another day: a painless path to longevity.

Steculorum, Sophie M; Brüning, Jens C · Cell · 2014

basic_science · Level V

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Abstract

Riera et al. identify a neuroendocrine circuit that controls longevity and the age-dependent onset of metabolic decline via the pain-transducing channel TRPV1. Thus, pharmacological inhibition of TRPV1 may provide a new approach to treat not only metabolic disorders but also a broader range of age-related pathologies.

Medical subject headings