Tempering temperature changes for robust development.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24855940.
- Also identified by DOI 10.1016/j.cell.2014.05.007.
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Abstract
Developmental signaling pathways needed to evolve to be robust against environmental fluctuations. In this issue, Shimizu et al. reveal a complex system of interacting endocytic pathways that help to maintain consistent levels of Notch activity across a range of temperatures.
Medical subject headings
- Drosophila Proteins
- Drosophila melanogaster
- Endocytosis
- Membrane Proteins
- Receptors, Notch
- Ubiquitin-Protein Ligases