Intestinal dysbiosis: novel mechanisms by which gut microbes trigger and prevent disease.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24857830.
- Also identified by DOI 10.1016/j.ypmed.2014.05.010.
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Abstract
New research has identified specific intestinal colonizing microbes that can have significant influence on health and disease. Evidence is reviewed supporting an association between Fusobacterium nucleatum and colon cancer and for a protective role of Faecalibacterium prausnitzii in inflammatory bowel disease, of Escherichia coli Nissle 1917 in acute intestinal inflammation, of Bifidobacterium infantis in neonatal necrotizing enterocolitis, and of Akkermansia muciniphila in obesity and diabetes. These novel bacteria are clinically relevant and present opportunities for more focused diagnosis of colon cancer and prevention of common diseases.
Medical subject headings
- Colorectal Neoplasms
- Dysbiosis
- Endotoxemia
- Enterocolitis, Necrotizing
- Inflammatory Bowel Diseases
- Insulin Resistance
- Intestines
- Obesity