Tools for chemical synthesis in microsystems.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24865228.
- Also identified by DOI 10.1039/c4lc00330f.
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Abstract
Chemical synthesis in microsystems has evolved from simple proof-of-principle examples to become a general technique in academia and industry. Numerous such "flow chemistry" applications are now found in pharmaceutical and fine chemical synthesis. Much of the development has been based on systems employing macroscopic flow components and tubes, rather than the integrated chip technology envisioned by the lab-on-a-chip community. We review the major developments in systems for flow chemistry and discuss limitations underlying the development of chip-scale integrated systems.
Medical subject headings
- Lab-On-A-Chip Devices
- Miniaturization