Tumor archaeology: tracking leukemic evolution to its origins.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24871129.
- Also identified by DOI 10.1126/scitranslmed.3009168.
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Abstract
Unearthing of the BRAF mutation in self-renewing hematopoietic stem cells reveals an unexpected origin for hairy cell leukemia-a mature B cell malignancy-and a potential new therapeutic target (Chung et al., this issue).
Medical subject headings
- Evolution, Molecular
- Leukemia