Thrombo-prevention in membranous nephropathy: a new tool for decision making?

Glassock, Richard J · Kidney Int · 2014

editorial · Level V

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Abstract

Thromboembolic events occur in primary membranous nephropathy, especially when serum albumin is less than 2.8 g/dl. In such patients, a conundrum arises concerning anticipated benefits and risks when a prophylactic oral anticoagulant is considered. Lee et al. describe a flexible Markov decision tree program to aid decision making. Its application to individual patients will probably be useful, but physicians will need to assess patients' tolerance for the benefit-to-risk ratio, considering the many factors bearing on the risk of thromboembolic events and/or serious bleeding.

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