Olfactory event-related potentials in infants.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24882499.
- Also identified by DOI 10.1016/j.jpeds.2014.04.033.
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Abstract
To evaluate olfactory event-related potentials (OERPs) as an objective measurement of olfactory function in infants. OERPs to phenylethyl alcohol were measured in 13 infants, between 23 and 41 days of age. The odor was delivered with a computer-controlled olfactometer. Recording electrodes were applied using the 10-20 system. Data from electrodes Fz, Cz, Pz, C3, and C4 were analyzed by MatLab's Letswave toolbox (André Mouraux, Brussels, Belgium) using the canonical time-domain averaging as well as the time-frequency analyzing method. Ten of 13 infants finished the recording session. We observed OERPs in 7 of these 10 infants. Recordings were best in electrodes Fz and Cz. The N1 peak was visible at 328 ms followed by P2 at 505 ms. In addition, the time-frequency analysis had an increase in low frequencies (4-7 Hz) around 550 ms after odor presentation. We were able to record OERPs in infants. The time-domain averaging as well as the time-frequency analysis was of value for data analysis.
Medical subject headings
- Evoked Potentials
- Smell