Father-son chats: inheriting stress through sperm RNA.
Level V
Where this comes from
- Record sourced from PubMed, PMID 24896534.
- Also identified by DOI 10.1016/j.cmet.2014.05.015 and PMC identifier 4131544.
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Abstract
Although mounting evidence in mammals suggests that certain ancestral environmental exposures can influence the phenotype in future generations, mechanisms underlying such intergenerational information transfer remain unclear. A recent report suggests that RNA isolated from sperm can inform offspring of a father's history of early life trauma (Gapp et al., 2014).
Medical subject headings
- MicroRNAs
- Spermatozoa
- Stress, Psychological