Disease progression in myelodysplastic syndromes: do mesenchymal cells pave the way?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24905157.
- Also identified by DOI 10.1016/j.stem.2014.05.010.
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Abstract
Early events driving the initiation and evolution of neoplasms remain poorly defined but involvement of an instructive or permissive niche has been implicated. In this issue of Cell Stem Cell, Medyouf et al. (2014) provide insights into the role of the niche in myelodysplastic syndromes, the principle preleukemic disorder of the hematopoietic system.
Medical subject headings
- Mesenchymal Stem Cells
- Myelodysplastic Syndromes
- Stem Cell Niche