A slow dance for microtubule acetylation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24906144.
- Also identified by DOI 10.1016/j.cell.2014.05.021.
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Abstract
Microtubules contribute to diverse cellular processes through balancing dynamic, short-lived and stable, long-lived populations. One way in which long-lived microtubules are marked is by posttranslational acetylation of α-tubulin by tubulin acetyltransferase (TAT). Szyk et al. now provide insight into TAT's mechanism of action and its unique time-stamping ability.
Medical subject headings
- Acetyltransferases
- Microtubules