Applying "gold standards" to in-vitro-derived germ cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24906145.
- Also identified by DOI 10.1016/j.cell.2014.05.019 and PMC identifier 4338014.
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Abstract
Germ cells are the ultimate stem cells, and reports of their in vitro derivation generate excitement due to potential applications in reproductive medicine. To date, there is no firm evidence that meiosis, the hallmark of gametogenesis, can be faithfully replicated outside of the gonad. We propose benchmarks for evaluating in vitro derivation of germ cells, facilitating realization of their potential.
Medical subject headings
- Cytological Techniques
- Gametogenesis
- Germ Cells
- Meiosis
- Stem Cells