Upconversion nanoparticles as a contrast agent for photoacoustic imaging in live mice.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24913756.
- Also identified by DOI 10.1002/adma.201400831.
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Abstract
An inclusion complex of NaYF4 :Yb(3+) ,Er(3+) upconversion nanoparticles with α-cyclodextrin in aqueous conditions exhibits luminescence quenching when excited at 980 nm. This non-radiative relaxation leads to an unprecedented photoacoustic signal enhancement. In vivo localization of α-cyclodextrin-covered NaYF4 :Yb(3+) ,Er(3+) is demonstrated using photoacoustic tomography in live mice, showing its high capability for photoacoustic imaging.
Medical subject headings
- Contrast Media
- Nanoparticles
- Photoacoustic Techniques
- Tomography