RNAi therapies: drugging the undruggable.

Wu, Sherry Y; Lopez-Berestein, Gabriel; Calin, George A; Sood, Anil K · Sci Transl Med · 2014

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Abstract

RNA interference (RNAi) therapy is a rapidly emerging platform for personalized cancer treatment. Recent advances in small interfering RNA delivery and target selection provide unprecedented opportunities for clinical translation. Here, we discuss these advances and present strategies for making RNAi-based therapy a viable part of cancer management.

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