Intrinsically germanium-69-labeled iron oxide nanoparticles: synthesis and in-vivo dual-modality PET/MR imaging.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24944166.
- Also identified by DOI 10.1002/adma.201401372 and PMC identifier 4127144.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Intrinsically germanium-69-labeled super-paramagnetic iron oxide nanoparticles are synthesized via a newly developed, fast and highly specific chelator-free approach. The biodistribution pattern and the feasibility of (69) Ge-SPION@PEG for in vivo dual-modality positron emission tomography/magnetic resonance (PET/MR) imaging and lymph-node mapping are investigated, which represents the first example of the successful utilization of a (69) Ge-based agent for PET/MR imaging.
Medical subject headings
- Germanium
- Magnetic Resonance Imaging
- Magnetite Nanoparticles
- Multimodal Imaging
- Positron-Emission Tomography
- Radioisotopes
- Whole Body Imaging