Prostate cancer SubtyPINg biomarKers and outcome: is clarity emERGing?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24944315.
- Also identified by DOI 10.1158/1078-0432.CCR-14-0818 and PMC identifier 4167216.
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Abstract
Molecular prostate cancer subtypes have been proposed on the basis of mutually exclusive SPINK1 and ERG overexpression, with conflicting reports on their prognostic ability. Flavin and colleagues report that SPINK1 is neither prognostic nor absolutely mutually exclusive with ERG, raising important questions about prostate cancer molecular subtyping and prognostic biomarker evaluation.
Medical subject headings
- Biomarkers, Tumor
- Prostatic Neoplasms