From cancer genomics to precision oncology--tissue's still an issue.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 24949964.
- Also identified by DOI 10.1016/j.cell.2014.05.027.
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Abstract
Rapidly evolving genome technology has enabled extensive molecular analysis of limited tumor biopsy material, thereby facilitating the broader implementation of personalized cancer medicine. However, genomics-based patient stratification across diverse tumor types is unlikely to supplant tissue-of-origin considerations in addressing clinical needs, including the development and application of novel "rationally targeted" cancer therapies.
Medical subject headings
- Neoplasms
- Precision Medicine