An overview of N-heterocyclic carbenes.

Hopkinson, Matthew N; Richter, Christian; Schedler, Michael; Glorius, Frank · Nature · 2014

review · Level V

Where this comes from

Abstract

The successful isolation and characterization of an N-heterocyclic carbene in 1991 opened up a new class of organic compounds for investigation. From these beginnings as academic curiosities, N-heterocyclic carbenes today rank among the most powerful tools in organic chemistry, with numerous applications in commercially important processes. Here we provide a concise overview of N-heterocyclic carbenes in modern chemistry, summarizing their general properties and uses and highlighting how these features are being exploited in a selection of pioneering recent studies.