Supercooling enables long-term transplantation survival following 4 days of liver preservation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24973919.
- Also identified by DOI 10.1038/nm.3588 and PMC identifier 4141719.
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Abstract
The realization of long-term human organ preservation will have groundbreaking effects on the current practice of transplantation. Herein we present a new technique based on subzero nonfreezing preservation and extracorporeal machine perfusion that allows transplantation of rat livers preserved for up to four days, thereby tripling the viable preservation duration.
Medical subject headings
- Cold Temperature
- Liver Transplantation
- Organ Preservation
- Survival Rate