Regulatory T cells and cancer: an undesired tolerance.
Level V
Where this comes from
- Record sourced from PubMed, PMID 24978377.
- Also identified by DOI 10.1038/ki.2014.46.
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Abstract
The incidence of cancer is markedly increased in organ transplant patients. A better understanding of underlying mechanisms and the identification of biomarkers for diagnosis and prognosis are major challenges. Hope et al. report expansion of regulatory T cells to be associated with the presence and severity of cancer. Although relevant, these results raise several questions.
Medical subject headings
- Kidney Transplantation
- Neoplasms
- T-Lymphocytes, Regulatory