Combining enzalutamide with abiraterone, prednisone, and androgen deprivation therapy in the STAMPEDE trial.

Attard, Gerhardt; Sydes, Matthew R; Mason, Malcolm D; Clarke, Noel W; Aebersold, Daniel; de Bono, Johann S; Dearnaley, David P; Parker, Chris C et al. · Eur Urol · 2014

editorial · Level V

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Abstract

There are compelling reasons to study the addition of both enzalutamide and abiraterone, in combination, to standard-of-care for hormone-naïve prostate cancer. Through a protocol amendment, this will be assessed in the STAMPEDE trial, with overall survival as primary outcome measure.

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