Brain endothelial cell targeting via a peptide-functionalized liposomal carrier for xenon hyper-CEST MRI.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24985966.
- Also identified by DOI 10.1002/adhm.201400224.
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Abstract
A nanoparticulate carrier system is used to efficiently deliver a contrast agent for highly sensitive xenon Hyper-CEST MRI. The carrier system not only improves the biocompatibility and solubility of the contrast agent, it also allows selective cell targeting as demonstrated by the discrimination of human brain capillary and aortic endothelial cells.
Medical subject headings
- Blood-Brain Barrier
- Endothelial Cells
- Magnetic Resonance Angiography
- Peptides