How far can mice carry autism research?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 24995974.
- Also identified by DOI 10.1016/j.cell.2014.06.032.
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Abstract
In the face of growing controversy about the utility of genetic mouse models of human disease, Rothwell et al. report on a shared mechanism by which two different neuroligin-3 mutations, associated with autism spectrum disorders in humans, produce an enhancement in motor learning. The open question is how much we can learn about human ills from such models.
Medical subject headings
- Autistic Disorder
- Cell Adhesion Molecules, Neuronal
- Membrane Proteins
- Nerve Tissue Proteins