Stem cells on alert: priming quiescent stem cells after remote injury.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 24996163.
- Also identified by DOI 10.1016/j.stem.2014.06.012.
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Abstract
A recent paper published by Rodgers et al. describes a novel phase of stem cell quiescence, termed GAlert, that serves to prime cells in response to injury-induced signals. These stem cells are located distal to the site of injury and require mTORC1 activity to elicit the alert response.
Medical subject headings
- Cell Cycle
- Multiprotein Complexes
- Muscle, Skeletal
- Resting Phase, Cell Cycle
- Satellite Cells, Skeletal Muscle
- TOR Serine-Threonine Kinases