Stressing out stem cells: linking stress and hematopoiesis in cardiovascular disease.

Hanna, Richard N; Hedrick, Catherine C · Nat Med · 2014

editorial · Level V

Where this comes from

Abstract

Stress has long been thought to be a major contributing factor to cardiovascular disease, although little is known about the underlying cellular mechanisms. A new study illustrates that chronic stress promotes hematopoietic stem cell proliferation in bone marrow, leading to increased leukocyte production, circulation, and recruitment to the vasculature.

Medical subject headings