Local anesthetic systemic toxicity.

Dickerson, David M; Apfelbaum, Jeffrey L · Aesthet Surg J · 2014

review · Level V

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Abstract

Local anesthetic systemic toxicity (LAST) is a rare yet devastating complication from the administration of local anesthesia. The ability to recognize and treat LAST is critical for clinicians who administer these drugs. The authors reviewed the literature on the mechanism, treatment, and prevention of LAST, with the goal of proposing a practical method for its management.

Medical subject headings