Cell and tissue engineering for liver disease.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25031271.
- Also identified by DOI 10.1126/scitranslmed.3005975 and PMC identifier 4374645.
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Abstract
Despite the tremendous hurdles presented by the complexity of the liver's structure and function, advances in liver physiology, stem cell biology and reprogramming, and the engineering of tissues and devices are accelerating the development of cell-based therapies for treating liver disease and liver failure. This State of the Art Review discusses both the near- and long-term prospects for such cell-based therapies and the unique challenges for clinical translation.
Medical subject headings
- Cell Engineering
- Liver Diseases
- Tissue Engineering