A new twist on transcriptional bursting.

Levens, David; Larson, Daniel R · Cell · 2014

basic_science · Level V

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Abstract

Transcriptional bursting has been observed across species and is one of the primary causes of variable gene expression in cells and tissue. In this issue, Chong et al. describe how DNA topology results in transcriptional bursting in E. coli.

Medical subject headings