Directing stem cell differentiation by changing the molecular mobility of supramolecular surfaces.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25044544.
- Also identified by DOI 10.1002/adhm.201400173.
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Abstract
Polymer surfaces with a wide range of hydrated surface mobility are developed by a simple deposition method with supramolecular block copolymers. The morphologies of adhering stem cells are greatly dependent on the surface mobility of polymers, and this induces significant changes in the cytoskeletal signaling pathway to direct the downstream stem cell differentiation.
Medical subject headings
- Cell Differentiation
- Mesenchymal Stem Cells