Glutamate metabolism in major depressive disorder.
Where this comes from
- Record sourced from PubMed, PMID 25073688.
- Also identified by DOI 10.1176/appi.ajp.2014.14010067 and PMC identifier 4472484.
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Abstract
Research on novel treatments for major depressive disorder focuses quite deeply on glutamate function, and this research would benefit from a brain-imaging technique that precisely quantified glutamate function. Signs of a specific form of glutamate-related dysfunction that could be targeted by novel therapies were found using novel, state-of-the-art techniques to address this issue.
Medical subject headings
- Adult
- Aged
- Carbon Isotopes
- Citric Acid Cycle
- Major Depressive Disorder
- Major Depressive Disorder/metabolism
- Female
- Glutamic Acid
- Glutamic Acid/metabolism
- Humans
- Magnetic Resonance Spectroscopy
- Magnetic Resonance Spectroscopy/methods
- Male
- Middle Aged
- Mitochondria
- Mitochondria/metabolism
- Models, Biological
- Neuroimaging
- Neuroimaging/methods
- Occipital Lobe
- Occipital Lobe/metabolism
- Protons
- Young Adult
- gamma-Aminobutyric Acid
- gamma-Aminobutyric Acid/metabolism