Chromatin biochemistry enters the next generation of code 'seq-ing'.

Shanle, Erin K; Rothbart, Scott B; Strahl, Brian D · Nat Methods · 2014

editorial · Level V

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Abstract

Barcoded semisynthetic nucleosomes combined with massively parallel sequencing provide an innovative new platform for analyzing the histone-recognition and histone-modifying activities of chromatin-associated proteins.

Medical subject headings