Hormone-sensitive lipase deficiency in humans.
Level V
Where this comes from
- Record sourced from PubMed, PMID 25100058.
- Also identified by DOI 10.1016/j.cmet.2014.07.018.
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Abstract
The breakdown of cellular fat stores fuels energy production and multiple anabolic processes. Albert et al. (2014) demonstrate that the lack of hormone-sensitive lipase, a member of the enzyme trio that catabolizes fat, has pronounced effects on lipid metabolism, glucose homeostasis, and cell signaling in humans.
Medical subject headings
- Diabetes Mellitus, Type 2
- Frameshift Mutation
- Genetic Predisposition to Disease
- Lipolysis
- Sterol Esterase