Another Shp on the horizon for bile acids.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25100060.
- Also identified by DOI 10.1016/j.cmet.2014.07.019.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Bile acid metabolism is tightly controlled due to the toxic effects of bile acid overload. In this issue, research from the Feng lab reports Shp2 as a novel integrator of hepatic bile acid and FGF15/FGF19 signaling, adding another layer of complexity to the control of bile acid biosynthesis.
Medical subject headings
- Bile Acids and Salts
- Liver
- Protein Tyrosine Phosphatase, Non-Receptor Type 11
- Signal Transduction