A local circadian clock calls time on lung inflammation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25100521.
- Also identified by DOI 10.1038/nm.3649.
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Abstract
Inflammatory diseases typically display circadian variation in symptom severity. A new study in mice shows how a pulmonary epithelial cell clock controls neutrophil recruitment to the lungs and provides insight into interactions between local and systemic circadian clocks.
Medical subject headings
- ARNTL Transcription Factors
- Chemokine CXCL5
- Circadian Clocks
- Glucocorticoids
- Pneumonia, Pneumococcal
- Streptococcus pneumoniae