Lightening up a notch: Notch regulation of energy metabolism.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25100522.
- Also identified by DOI 10.1038/nm.3650 and PMC identifier 4431689.
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Abstract
Inhibiting Notch signaling induces adipose browning, improves systemic glucose tolerance and insulin sensitivity, and suppresses weight gain in mice.
Medical subject headings
- Adipose Tissue, Brown
- Adipose Tissue, White
- Immunoglobulin J Recombination Signal Sequence-Binding Protein
- Obesity
- Receptor, Notch1