Another brick in the wall: RNAi Screens identify new barriers in iPSC reprogramming.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25105575.
- Also identified by DOI 10.1016/j.stem.2014.07.008.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Somatic cells can be reprogrammed to induced pluripotent stem cells via exogenous expression of a small set of transcription factors, but the regulatory mechanisms controlling this cell transition are poorly understood. Two recent reports demonstrate the value of RNAi screens as a tool to uncover roadblocks in this inefficient process.
Medical subject headings
- Cellular Reprogramming
- Induced Pluripotent Stem Cells