Eyes on the prize: limbal stem cells and corneal restoration.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25105577.
- Also identified by DOI 10.1016/j.stem.2014.07.011.
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Abstract
Corneal diseases and blindness can result from deficiency in limbal stem cells, and autologous transplantation is often the only therapeutic option. Two recent studies in Nature have provided insights into regulation of limbal stem cell function and corneal regeneration and present new opportunities for clinical interventions in eye diseases.
Medical subject headings
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- ATP-Binding Cassette Transporters
- Corneal Diseases
- Epithelium, Corneal
- Eye Proteins
- Homeodomain Proteins
- Homeostasis
- Limbus Corneae
- Paired Box Transcription Factors
- Regeneration
- Repressor Proteins
- Stem Cells
- Wnt Proteins
- Wound Healing