Dye-loaded ferritin nanocages for multimodal imaging and photothermal therapy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25123089.
- Also identified by DOI 10.1002/adma.201400914 and PMC identifier 4215197.
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Abstract
Multimodal imaging-guided photothermal therapy (PTT), for the therapy of cancer, based on a ferritin (FRT) nanocage loaded with the near-infrared dye IR820 (designated DFRT) is demonstrated. The dual roles of DFRT (in imaging and PTT) are successfully balanced by using two different excitation wavelengths: 550 nm for high quantum-yield fluorescence imaging on the one hand and 808 nm for photoacoustic imaging and PTT with high photothermal conversion efficiency on the other.
Medical subject headings
- Ferritins
- Fluorescent Dyes
- Nanostructures