A smart "sense-act-treat" system: combining a ratiometric pH sensor with a near infrared therapeutic gold nanocage.

Shi, Peng; Liu, Zhen; Dong, Kai; Ju, Enguo; Ren, Jinsong; Du, Yingda; Li, Zhengqiang; Qu, Xiaogang · Adv Mater · 2014

basic_science · Level V

Where this comes from

Abstract

Herein, we design a "sense-act-treat" system via the combination of a ratiometric pH sensor with a therapeutic gold nanocage. Our design could "sense" the tumor through two-state switching of fluorescence and further provide chemotherapy and hyperthermia for "treating" the tumor, showing the potential for future biomedical applications.

Medical subject headings