Mouse models of human cancer.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25136075.
- Also identified by DOI 10.1158/0008-5472.CAN-14-1424.
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Abstract
The Helmholtz Alliance Preclinical Comprehensive Cancer Center (PCCC; www.helmholtz-pccc.de) hosted the "1st International Kloster Seeon Meeting on Mouse Models of Human Cancer" in the Seeon monastery (Germany) from March 8 to 11, 2014. The meeting focused on the development and application of novel mouse models in tumor research and high-throughput technologies to overcome one of the most critical bottlenecks in translational bench-to-bedside tumor biology research. Moreover, the participants discussed basic molecular mechanisms underlying tumor initiation, progression, metastasis, and therapy resistance, which are the prerequisite for the development of novel treatment strategies and clinical applications in cancer therapy.
Medical subject headings
- Disease Models, Animal
- Mice
- Neoplasms