History of vaccination.

Plotkin, Stanley · Proc Natl Acad Sci U S A · 2014

Level V

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Abstract

Vaccines have a history that started late in the 18th century. From the late 19th century, vaccines could be developed in the laboratory. However, in the 20th century, it became possible to develop vaccines based on immunologic markers. In the 21st century, molecular biology permits vaccine development that was not possible before.

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