High usage of topical fusidic acid and rapid clonal expansion of fusidic acid-resistant Staphylococcus aureus: a cautionary tale.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 25139961.
- Also identified by DOI 10.1093/cid/ciu658.
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Abstract
Our aim was to assess national prescribing trends and determine longitudinal resistance patterns for topical antimicrobials in New Zealand. We observed a dramatic increase in fusidic acid (FA) resistance, and clonal expansion of FA-resistant Staphylococcus aureus. This increase was concurrent with a significant national increase in topical FA dispensing.
Medical subject headings
- Anti-Bacterial Agents
- Drug Prescriptions
- Drug Resistance, Bacterial
- Fusidic Acid
- Staphylococcal Infections
- Staphylococcus aureus