Amphiphilic star copolymer-based bimodal fluorogenic/magnetic resonance probes for concomitant bacteria detection and inhibition.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25147084.
- Also identified by DOI 10.1002/adma.201402797.
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Abstract
Four-arm star-shaped copolymers, TPE-star-P(DMA-co-BMA-co-Gd), containing TPE cores with an aggregation-induced emission (AIE) feature, a T 1 -type magnetic resonance (MR) contrast agent, and amphiphilic cationic arms, are synthesized. By taking advantage of non-covalent interactions between star copolymers and bacteria surfaces, bimodal fluorometric/MR detection and concomitant inhibition of both Gram-positive and Gram-negative bacteria strains in aqueous media are explored.
Medical subject headings
- Escherichia coli
- Hydrophobic and Hydrophilic Interactions
- Magnetic Phenomena
- Polymers