Science to Practice: Highly shifted proton MR imaging--a shift toward better cell tracking?
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 25153271.
- Also identified by DOI 10.1148/radiol.14141410 and PMC identifier 4321787.
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Abstract
Summary A "hot spot" magnetic resonance (MR) imaging cell tracking technique has been developed that allows direct detection of dysprosium- or thulium-1,4,7,10-tetraazacyclododecane-α,α',α'',α'''-tetramethyl-1,4,7,10-tetraacetic acid (DOTMA)-labeled protons inside cells. These highly shifted protons may allow specific detection of multiple cell types because it does not rely on acquiring the proton signal from bulk water.
Medical subject headings
- Cell Tracking
- Fibrosarcoma
- Granuloma
- Image Enhancement
- Macrophages
- Magnetic Resonance Imaging
- Quaternary Ammonium Compounds