Neutralizing the HIV reservoir.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25171398.
- Also identified by DOI 10.1016/j.cell.2014.08.010 and PMC identifier 4182933.
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Abstract
Halper-Stromberg et al. use a humanized mouse model to demonstrate that broadly neutralizing antibodies, when administered with a combination of HIV latency activators, can reduce persistent HIV reservoirs, as measured by plasma virus rebound. Their results support the use of broadly neutralizing antibodies in HIV-reservoir-purging strategies.
Medical subject headings
- Antibodies, Neutralizing
- HIV Infections
- HIV-1
- Transcription, Genetic
- Virus Latency