Emerging roles of RNA modification: m(6)A and U-tail.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25171402.
- Also identified by DOI 10.1016/j.cell.2014.08.005.
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Abstract
Although more than 100 types of RNA modification have been described thus far, most of them were thought to be rare in mRNAs and in regulatory noncoding RNAs. Recent developments have unveiled that at least some of the modifications are considerably abundant and widely conserved. This Minireview summarizes the molecular machineries and biological functions of methylation (N6-methyladenosine, m(6)A) and uridylation (U-tail).
Medical subject headings
- RNA Processing, Post-Transcriptional
- RNA, Messenger