Switchable water-adhesive, superhydrophobic palladium-layered silicon nanowires potentiate the angiogenic efficacy of human stem cell spheroids.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25183387.
- Also identified by DOI 10.1002/adma.201402273.
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Abstract
A switchable water-adhesive, super-hydrophobic nanowire surface is developed for the formation of functional stem cell spheroids. The sizes of hADSC spheroids are readily controllable on the surface. Our surface increases cell-cell and cell-matrix interaction, which improves viability and paracrine secretion of the spheroids. Accordingly, the hADSC spheroids produced on the surface exhibit significantly enhanced angiogenic efficacy.
Medical subject headings
- Nanowires
- Neovascularization, Physiologic
- Palladium
- Silicon
- Spheroids, Cellular
- Stem Cells
- Water